Table 4.
Associations between obesity and mechanical ventilation requirement among children with dengue shock syndrome.
| Factors | MV (n = 112) | Non-MV (n = 746) | Crude OR (95% CI), P* | Adjusted OR (95% CI), P† |
|---|---|---|---|---|
| Obesity | ||||
| No Yes |
81 (72.3) 31 (27.7) |
587 (78.7) 159 (21.3) |
1.41 (0.90–2.21), P = .13 |
2.3 (1.31–4.06), P < .01 |
| Age (years), median (IQR) | 7 (5–10) | 7 (5–10) | 0.97 (0.92–1.02), P = .27 |
- |
| Gender | ||||
| Male Female |
52 (46.4) 60 (53.6) |
402 (53.9) 344 (46.1) |
1.35 (0.91–2.01), P = .14 |
1.75 (1.04–2.93), P = .03 |
| Severe bleeding‡ | ||||
| No Yes |
65 (58) 47 (42) |
725 (97) 21 (3) |
24.8 (14.0–44.0), P < .001 |
16.8 (8.61–32.7), P < .001 |
| Hematocrit (%), median (IQR) | 45 (40–50) | 48 (45–51) | 0.9 (0.87–0.93), P < .001 |
0.91 (0.87–0.95), P < .001 |
| Low platelet count (<20,000 cells × 109/L) | - | |||
| No Yes |
81 (72.3) 31 (27.7) |
635 (85.1) 111 (14.9) |
2.16 (1.36–3.42), P = .001 |
|
| Severe hepatic transaminases‡ | ||||
| No Yes |
76 (67.9) 36 (32.1) |
674 (90.3) 72 (9.7) |
4.43 (2.79–7.06), P < .001 |
2.99 (1.56–5.74), P = .001 |
| Square root of cumulative infused fluid from referral hospitals and 24 hours PICU admission (mL/kg)§ | 13.1 (10.3–15.3) | 9.4 (0–11.7) | 1.15 (1.1–1.20), P < .001 |
1.15 (1.1–1.21), P < .001 |
CI = confidence interval; IQR = interquartile range; MV = mechanical ventilation; OR = odds ratio; PICU = pediatric intensive care unit.
*
Crude OR and P-values from bivariate logistic analyses.
†
Adjusted OR and P-values from multivariable logistic analyses.
‡
These factors were defined by the WHO dengue guidelines in 2009.
§
Standardized covariate of the cumulative amount of fluid from referral hospitals and within 24h PICU admission by square root.