Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 21;223(1):e202305048. doi: 10.1083/jcb.202305048

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Tiwari et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure S2. — (Related to Fig. 3). Sirt3 regulates mitochondrial morphology in hippocampal axons. (A) Relative expression of sirt3 mRNA in control and Sir3 KD cortical neurons. Values are normalized to β-actin mRNA and expressed relative to the control. Average normalized mRNA level ± SEM: Sirt3 KD, 0.19 ± 0.07. n = 4 cortical samples. (B) Hippocampal axons from control and Sirt3 KD neurons expressing the mitochondrial marker mito^4x-RFP. (C) Mitochondria length in control and Sirt3 KD axons. Mean length per neuronal axon (μm) ± SEM: control, 2.0 ± 0.03, Sirt3 KD, 1.6 ± 0.03. n = 31–42 neurons. Two-tailed, unpaired t test (A and C).