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Table 2.

Comparison of some hematological parameters among patients with leprosy and controls

Variable Control subjects n=30 Patients with leprosy on MDT n=30 Patients with leprosy that had completed MDT n=30 p-value F ratio / H df Eta squared
*RBC (×1012/L) 4.72 ± 0.65a 4.19 ± 0.75b 3.93 ± 0.49b <0.010 12.331 2 0.219
*Hemoglobin (g/dL) 14.01 ± 1.49a 12.67 ± 2.55b 11.21 ± 2.00c <0.010 13.822 2 0.241
*Hematocrit (L/L) 0.41 ± 0.045a 0.38 ± 0.07b 0.33 ± 0.05b <0.01 14.417 2 0.249
MCV (fL) 88.70 (86.00 – 91.70)a,b 92.85 (87.07 – 94.55)b 86.10 (78.20 – 92.40)a 0.023 7.587 2 0.091
MCH (pg) 29.90 (28.80 – 31.90) 30.45 (28.62 – 32.02) 29.5 (32.90 – 34.30) 0.284 2.518 2 0.040
MCHC (g/dL) 33.90 (33.60 – 34.50)a 33.20 (32.50 – 33.65)b 33.90 (32.50 – 33.65)a <0.010 15.430 2 0.136
RDW (%) 13.30 (13.0 – 14.20)a 14.15 (13.22 – 15.35)b 14.90 (14.10 – 16.60)b <0.010 15.543 2 0.150
TWBC (×109/L) 4.50 (3.90 – 5.40)a 6.20 (4.93 – 8.10)b 7.30 (5.50 – 9.00)b <0.010 24.495 2 0.209
Lymphocytes (×109/L) 2.03 (1.81 – 2.61)a 2.42 (1.82 – 3.05)a,b 2.57 (5.50 – 9.00)b 0.030 7.023 2 0.066
Neutrophil s(×109/L) 1.77 (1.36 – 2.39)a 2.72 (1.72 – 4.18)b 3.11 (2.15 – 4.37)b <0.010 15.435 2 0.151
Monocytes (×109/L) 0.30 (0.27 – 0.40)a 0.47 (0.4 – 0.64)b 0.51 (0.43 – 0.70)b <0.010 26.821 2 0.152
Eosinophils (×109/L) 0.15 (0.13 – 0.26)a 0.24 (0.09 – 0.52)b 0.31 (0.21 – 0.58)b 0.004 11.056 2 0.042
Basophils (×109/L) 0.01 (0.01 – 0.02) 0.01 (0.01 – 0.03) 0.02 (0.02 – 0.03) 0.059 5.651 2 0.043
N/L ratio 0.92 (0.72 – 1.09) 1.12 (0.75 – 1.55) 1.12 (0.75 – 1.55) 0.090 4.811 2 0.065
Platelets (×109/L) 195.00 (174.00 - 225.00) 236.00 (180.75 – 277.75) 210.00 (165.00 – 251.00) 0.089 4.842 2 0.064
MPV (fL) 8.30 (8.10 – 8.60) 8.45 (7.70 – 8.95) 7.90 (7.50 – 8.40) 0.094 4.726 2 0.070
*

Refers to mean ± SD and reported F ratio of ANOVA.

Refers to median (interquartile range) and reports corresponding Kruskal Wallis H.

RBC – red cell count; MCV – mean corpuscular volume; MCH – mean corpuscular hemoglobin; MCHC – mean corpuscular hemoglobin concentration; RDW – red cell distribution width; N/L ratio – neutrophil to lymphocyte ratio; MPV – mean platelet volume; MDT – multidrug therapy; cMDT – completed MDT.