Table 3.

Response to platinum-based chemotherapy according to p-BRCA mutation in the tumor tissue

Response	p-BRCA mutations and LOH status			p-value
	LOH+	LOH–	Wild
Complete response	1 (6.3)	1 (4.2)	5 (3.3)	.001a
Partial response	15 (93.8)	8 (33.3)	86 (57.3)
Stable disease	0	12 (50.0)	52 (34.7)
Progressive disease	0	3 (12.5)	7 (4.7)
Total	16	24	150

Values are presented as number (%).

p-BRCA mutation, pathogenic or likely pathogenic BRCA1 or BRCA2 gene mutation; LOH, loss of heterozygosity.

^aKruskal-Wallis test.