TABLE 1.
Baseline characteristics of hairy cell leukemia (HCL) patients.
Baseline characteristics (N = 14) | |
---|---|
Age at HCL diagnosis, median (range) | 47 (23–67) |
Sex, n (%) | |
Female | 4 (28.6) |
Male | 10 (71.4) |
COVID‐19 diagnosis and vaccination status | |
---|---|
Vaccinated, n (%) | |
No | 3 (21.4) |
Yes | 11 (78.6) |
First vaccination before positive COVID‐19 testing | 5 (35.7) |
First vaccination after positive COVID‐19 testing | 6 (42.9) |
Vaccination dose and type, n (%) (n = 11) | |
One dose: Moderna | 1 (9.1) |
Two doses (same product): | 5 (45.5) |
Moderna | 2 |
Pfizer | 2 |
Janssen | 1 |
Three doses: | 5 (45.5) |
Moderna | 2 |
Pfizer | 3 (1 previously received Janssen) |
HCL treatment history | |
---|---|
Has HCL been treated, n (%) | |
No | 3 (21.4) |
Yes | 11 (78.6) |
Number of lines of prior treatment (n = 11) | |
Median (range) | 2 (1–4) |
On Tx at COVID‐19 dx?, n (%) | |
No | 9 (81.8) |
Yes | 2 (18.2) |
NA | 2 |
Last IgG level prior to COVID‐19 Dx | |
Median (range) | 988 (728–1216) |
NA | 8 |
Last CD4 count | |
Median (range) | 349 (259–460) |
NA | 9 |
Last CD8 count | |
Median (range) | 157 (112–380) |
NA | 9 |
Management of COVID‐19 | |
---|---|
Treatment, n (%) | |
Monoclonal antibody a | 7 (50) |
Remdesivir | 1 (7.1) |
Other b | 2 (28.6) |
Abbreviations: IgG, immunoglobulin G; NA, not available.
Monoclonal antibody received: casirivimab, imdevimab (n = 1), sotrovimab (n = 2), and bamlanivimab (n = 2).
Other treatments: antibiotics (n = 1) and Paxlovid (n = 1).