Table 2.
Multinomial logistic regression analysis exploiting ORs-like to evaluate patient clinical features as predictive factor of different cluster membership
| ORs-like | SE | 95% CI | P value | |
| Cluster 1: ‘Juvenile/Transitional’ | ||||
| Male sex | 0.59 | 0.17 | 0.33 to 1.04 | 0.067 |
| Arthralgia | 0.90 | 0.40 | 0.37 to 2.16 | 0.809 |
| Arthritis | 0.62 | 0.19 | 0.34 to 1.15 | 0.130 |
| Skin rash | 1.87 | 0.56 | 1.04 to 3.38 | 0.037 |
| Sore throat | 1.89 | 0.55 | 1.07 to 3.34 | 0.027 |
| Myalgia | 2.25 | 0.67 | 1.25 to 4.05 | 0.007 |
| Lymph node involvement | 1.61 | 0.46 | 0.92 to 2.84 | 0.096 |
| Liver involvement | 1.17 | 0.36 | 0.64 to 2.14 | 0.597 |
| Spleen involvement | 1.94 | 0.60 | 1.06 to 3.57 | 0.032 |
| Pericarditis | 1.03 | 0.48 | 0.41 to 2.59 | 0.943 |
| Pleuritis | 1.02 | 0.51 | 0.38 to 2.71 | 0.974 |
| Abdominal pain | 1.47 | 0.60 | 0.66 to 3.27 | 0.347 |
| MAS | 3.67 | 1.84 | 1.37 to 9.82 | 0.010 |
| Lung disease | 1.24 | 0.78 | 0.36 to 4.25 | 0.730 |
| Cluster 2: ‘Uncomplicated’ | ||||
| Base outcome | ||||
| Cluster 3: ‘Hyperferritinemic’ | ||||
| Male sex | 0.42 | 0.20 | 0.17 to 1.05 | 0.063 |
| Arthralgia | 0.56 | 0.35 | 0.17 to 1.89 | 0.352 |
| Arthritis | 0.57 | 0.27 | 0.23 to 1.44 | 0.237 |
| Skin rash | 1.51 | 0.70 | 0.61 to 3.72 | 0.373 |
| Sore throat | 1.51 | 0.67 | 0.63 to 3.61 | 0.354 |
| Myalgia | 1.35 | 0.60 | 0.56 to 3.23 | 0.507 |
| Lymph node involvement | 1.22 | 0.54 | 0.51 to 2.91 | 0.653 |
| Liver involvement | 2.21 | 1.04 | 0.88 to 5.54 | 0.090 |
| Spleen involvement | 0.71 | 0.35 | 0.27 to 1.85 | 0.481 |
| Pericarditis | 1.78 | 1.12 | 0.52 to 6.09 | 0.354 |
| Pleuritis | 1.32 | 0.87 | 0.36 to 4.82 | 0.677 |
| Abdominal pain | 0.83 | 0.59 | 0.21 to 3.30 | 0.796 |
| MAS | 4.65 | 2.89 | 1.38 to 15.70 | 0.013 |
| Lung disease | 1.03 | 0.96 | 0.17 to 6.40 | 0.971 |
| Cluster 4: ‘Catastrophic’ | ||||
| Male sex | 0.99 | 0.34 | 0.51 to 1.92 | 0.966 |
| Arthralgia | 0.40 | 0.19 | 0.15 to 1.03 | 0.058 |
| Arthritis | 0.74 | 0.28 | 0.35 to 1.56 | 0.432 |
| Skin rash | 2.07 | 0.76 | 1.00 to 4.27 | 0.050 |
| Sore throat | 3.03 | 1.09 | 1.50 to 6.15 | 0.002 |
| Myalgia | 2.56 | 0.92 | 1.26 to 5.18 | 0.009 |
| Lymph node involvement | 1.96 | 0.68 | 0.99 to 3.88 | 0.055 |
| Liver involvement | 2.29 | 0.85 | 1.11 to 4.75 | 0.025 |
| Spleen involvement | 1.81 | 0.67 | 0.88 to 3.72 | 0.106 |
| Pericarditis | 1.57 | 0.78 | 0.59 to 4.14 | 0.364 |
| Pleuritis | 2.21 | 1.13 | 0.81 to 6.01 | 0.121 |
| Abdominal pain | 0.93 | 0.47 | 0.34 to 2.51 | 0.879 |
| MAS | 3.20 | 1.77 | 1.08 to 9.48 | 0.036 |
| Lung disease | 2.86 | 1.76 | 0.85 to 9.54 | 0.088 |
| χ2 = 108.59; p<0.0001 | ||||
Bold values are statistically significant results.
MAS, macrophage activation syndrome.