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. 2023 Nov 6;9(6):69. doi: 10.3390/ncrna9060069

Figure 5.

Figure 5

Long 5′-tRFs and 5′-tRHs from the nuclear trna10_LysCTT (hg19: chr16, forward strand, 3241501-3241573) in brain samples and glioblastoma model cell lines. In control patient brain samples, patient glioblastoma samples, and the glioblastoma cell lines Gli36, U87-MG, T98G, and U251, tRFs SRR10803543, SRR10803544, and SRR10803545 were subjected to hypoxia and Hif1a knock-out. Samples SRR10803546, SRR10803547, and SRR10803548 were subjected to hypoxia and Hif2a knock-out. Samples SRR10803549, SRR10803550, and SRR10803551 were subjected to hypoxia, Hif1a knock-out, and Hif2a knock-out. Samples SRR6928219 and SRR6928223 were treated with EZH2 knock-out and VP55 overexpression. Samples SRR6928220 and SRR6928224 were treated with VP55 overexpression. Samples SRR6928236 and SRR6928237 were treated with EZH2 knock-out. The other samples were untreated. To enable comparisons, formatting, highlighting, conditional coloring, and thresholding are exactly as in Figure 2.