Table 2. Crude and adjusted logistic regression between psoriasis and thyroid function variables (n = 9649).
Crude | Model 1 | Model 2 | ||
---|---|---|---|---|
TSH | ||||
lnTSH, per unit (mIU/L) | 1.27 (1.02-1.58)* | 1.22 (0.97-1.52) | 1.24 (0.99-1.56) | |
1st quintile | 0.68 (0.45-1.01) | 0.71 (0.47-1.07) | 0.69 (0.46-1.04) | |
2nd quintile | 0.84 (0.57-1.22) | 0.86 (0.59-1.26) | 0.85 (0.58-1.25) | |
3rd quintile | Ref | Ref | Ref | |
4th quintile | 1.06 (0.74-1.52) | 1.04 (0.72-1.49) | 1.04 (0.73-1.50) | |
5th quintile | 0.92 (0.64-1.34) | 0.90 (0.62-1.31) | 0.91 (0.63-1.33) | |
FT4 | ||||
lnFT4, per unit (ng/dL) | 1.12 (0.47-2.67) | 1.00 (0.42-2.41) | 0.99 (0.41-2.37) | |
1st quintile | 1.19 (0.78-1.79) | 1.19 (0.79-1.80) | 1.17 (0.77-1.77) | |
2nd quintile | 1.32 (0.89-1.96) | 1.32 (0.89-1.96) | 1.31 (0.88-1.94) | |
3rd quintile | Ref | Ref | Ref | |
4th quintile | 1.06 (0.70-1.60) | 1.01 (0.66-1.53) | 1.00 (0.65-1.51) | |
5th quintile | 1.35 (0.91-2.00) | 1.29 (0.87-1.92) | 1.27 (0.86-1.88) | |
FT3 | ||||
lnFT3, per unit (ng/dL) | 0.55 (0.21-1.45) | 0.60 (0.22-1.69) | 0.58 (0.21-1.62) | |
1st quintile | 1.61 (1.09-2.38)* | 1.65 (1.11-2.46)* | 1.66 (1.11-2.46)* | |
2nd quintile | 1.46 (0.99-2.15) | 1.47 (0.99-2.18) | 1.47 (0.99-2.17) | |
3rd quintile | Ref | Ref | Ref | |
4th quintile | 0.98 (0.64-1.50) | 1.00 (0.65-1.54) | 1.00 (0.65-1.53) | |
5th quintile | 1.40 (0.96-2.04) | 1.48 (1.01-2.17)* | 1.46 (0.99-2.14) | |
TPOAb | ||||
Negative | Ref | Ref | Ref | |
Positive (≥34 IU/mL) | 0.75 (0.45-1.22) | 0.73 (0.44-1.22) | 0.73 (0.44-1.23) | |
Subclinical hypothyroidism | ||||
No | Ref | Ref | Ref | |
Yes | 1.11 (0.77-1.61) | 1.10 (0.76-1.60) | 1.12 (0.77-1.63) |
p < 0.05;
p < 0.01.
Ref: reference category; ln: natural log transformed; TSH: thyroid-stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPOAb: thyroid peroxidase antibodies. Adjustments: Model 1: sex, age, race/ethnicity, education; Model 2: model 1+ smoking.