Table 4. Crude and adjusted logistic regression between psoriasis and thyroid function variables, after exclusion of patients reporting cardiovascular disease, diabetes and inflammatory diseases at baseline (n = 7608; psoriasis n = 201).
Crude | Model 2 | ||
---|---|---|---|
TSH | |||
lnTSH, per unit (mIU/L) | 1.42 (1.09-1.84)* | 1.40 (1.07-1.83)* | |
1st quintile | 0.63 (0.39-1.01) | 0.62 (0.38-1.00)* | |
2nd quintile | 0.82 (0.53-1.28) | 0.82 (0.53-1.27) | |
3rd quintile | Ref | Ref | |
4th quintile | 0.94 (0.62-1.43) | 0.90 (0.59-1.38) | |
5th quintile | 1.06 (0.70-1.60) | 1.03 (0.68-1.56) | |
FT4 | |||
lnFT4, per unit (ng/dL) | 1.36 (0.49-3.77) | 1.19 (0.43-3.29) | |
1st quintile | 1.20 (0.76-1.90) | 1.18 (0.74-1.87) | |
2nd quintile | 1.13 (0.72-1.78) | 1.11 (0.70-1.75) | |
3rd quintile | Ref | Ref | |
4th quintile | 0.97 (0.60-1.56) | 0.88 (0.54-1.43) | |
5th quintile | 1.39 (0.89-2.17) | 1.30 (0.83-2.04) | |
FT3 | |||
lnFT3, per unit (ng/dL) | 0.46 (0.15-1.45) | 0.44 (0.13-1.50) | |
1st quintile | 1.64 (1.04-2.58)* | 1.71 (1.07-2.73)* | |
2nd quintile | 1.56 (1.00-2.43) | 1.60 (1.02-2.51)* | |
3rd quintile | Ref | Ref | |
4th quintile | 0.92 (0.56-1.51) | 0.92 (0.56-1.52) | |
5th quintile | 1.37 (0.89-2.11) | 1.40 (0.90-2.18) | |
TPOAb | |||
Negative | Ref | Ref | |
Positive (≥ 34 IU/mL) | 0.69 (0.39-1.25) | 0.72 (0.40-1.30) | |
Subclinical hypothyroidism | |||
No | Ref | Ref | |
Yes | 1.37 (0.91-2.05) | 1.36 (0.90-2.06) |
p < 0.05;
p < 0.01.
Ref: reference category; ln: natural log transformed; TSH: thyroid-stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPOAb: thyroid peroxidase antibodies. Model 2 was adjusted for sex, age, race/ethnicity, education, and smoking.