Table 5. Crude and adjusted logistic regression between psoriasis and thyroid function variables, excluding participants with TSH > 10 mIU/L (n = 9630).
| Crude | Model 2 | ||
|---|---|---|---|
| TSH | |||
| lnTSH, per unit (mIU/L) | 1.29 (1.03-1.61)* | 1.27 (1.01-1.59)* | |
| 1st quintile | 0.68 (0.45-1.01) | 0.69 (0.46-1.04) | |
| 2nd quintile | 0.84 (0.57-1.22) | 0.85 (0.58-1.25) | |
| 3rd quintile | Ref | Ref | |
| 4th quintile | 1.06 (0.74-1.52) | 1.04 (0.73-1.50) | |
| 5th quintile | 0.93 (0.65-1.35) | 0.92 (0.63-1.34) | |
| FT4 | |||
| lnFT4, per unit (ng/dL) | 1.12 (0.47-2.66) | 0.98 (0.41-2.35) | |
| 1st quintile | 1.19 (0.79-1.80) | 1.18 (0.78-1.78) | |
| 2nd quintile | 1.32 (0.89-1.96) | 1.31 (0.88-1.94) | |
| 3rd quintile | Ref | Ref | |
| 4th quintile | 1.06 (0.70-1.60) | 1.00 (0.65-1.51) | |
| 5th quintile | 1.35 (0.91-1.99) | 1.27 (0.85-1.88) | |
| FT3 | |||
| lnFT3, per unit (ng/dL) | 0.55 (0.21-1.45) | 0.58 (0.21-1.62) | |
| 1st quintile | 1.61 (1.09-2.38)* | 1.65 (1.11-2.46)* | |
| 2nd quintile | 1.46 (0.99-2.15) | 1.47 (0.99-2.17) | |
| 3rd quintile | Ref | Ref | |
| 4th quintile | 0.98 (0.64-1.50) | 1.00 (0.65-1.53) | |
| 5th quintile | 1.40 (0.96-2.03) | 1.46 (0.99-2.14) | |
| TPOAb | |||
| Negative | Ref | Ref | |
| Positive (≥34 IU/mL) | 0.75 (0.46-1.23) | 0.74 (0.44-1.23) | |
| Subclinical hypothyroidism | |||
| No | Ref | Ref | |
| Yes | 1.13 (0.78-1.64) | 1.14 (0.78-1.66) | |
*
p < 0.05;
**
p < 0.01.
Ref: reference category; ln: natural log transformed; TSH: thyroid-stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPOAb: thyroid peroxidase antibodies. Model 2 was adjusted for sex, age, race/ethnicity, education, and smoking.