Table 1.
Clinical characteristics of pregnant women with ICP and healthy pregnant controls.
| Variable | Screening Samples |
Validation Samples |
||||
|---|---|---|---|---|---|---|
| Control(n = 8) | ICP(n = 8) | P value | Control(n = 20) | ICP(n = 20) | P value | |
| Maternal age(years) | 32.4 ± 4.9 | 31.4 ± 5.0 | 1.000 | 32.5 ± 5.6 | 31.6 ± 4.7 | 0.570 |
| Delivery weeks | 39.1 ± 0.4 | 37.0 ± 1.1 | 0.024* | 39.3 ± 0.7 | 37.0 ± 1.6 | 0.004* |
| TBA(μmol/L) | 2.7 ± 0.8 | 65.2 ± 48.2 | 0.005* | 4.0 ± 2.0 | 53.0 ± 39.1 | 0.000* |
| ALT(IU/L) | 9.1 ± 1.6 | 102.0 ± 69.5 | 0.000* | 11.1 ± 7.0 | 102.0 ± 85.5 | 0.000* |
| AST(IU/L) | 16.4 ± 3.4 | 67.8 ± 39.4 | 0.004* | 18.2 ± 4.6 | 73.3 ± 61.7 | 0.000* |
| ALP(IU/L) | 153.7 ± 65.2 | 236.1 ± 36.2 | 0.334 | 155.9 ± 57.4 | 216.8 ± 56.0 | 0.889 |
| TBIL(μmol/L) | 8.3 ± 3.1 | 14.8 ± 12.2 | 0.156 | 9.1 ± 3.1 | 12.3 ± 8.3 | 0.142 |
| DBIL(μmol/L) | 2.2 ± 1.0 | 7.8 ± 9.8 | 0.063 | 2.3 ± 0.9 | 5.6 ± 6.4 | 0.058 |
| Newborn weight(g) | 3391.3 ± 563.6 | 2914.4 ± 453.5 | 0.451 | 3579.5 ± 484.1 | 2975.0 ± 461.3 | 0.983 |