Table 4:

Whole Body 18F-FDG PET/CT and PET/MRI protocol for whole-body assessment of extrapulmonary metastases.

Study name	Patient prep	Radiopharmaceutical	Dose range	Delivery	Time from dose to imaging	Imaging acquisition	Comment
18F-FDG PET/CT	- NPO for 4–6 hours to decrease serum glucose and insulin levels. - Stop all IV dextrose 4 hours prior to 18F-FDG administration - Warm the patient for 30–60 minutes prior to 18F-FDG administration to minimize uptake in brown adipose tissue.	18F-Fluorodeoxyglucose (FDG)	0.10–0.14 mCi/kg Minimum dose 0.7 mCi	Intravenous	60 ± 10 minutes	PET/CT CT performed with appropriate pediatric CT settings.	True whole-body field of view recommended (skull vertex to feet).
18F-FDG PET/MRI	Same	18F-Fluorodeoxyglucose (FDG)	0.08 mCi/kg Minimum dose 0.7 mCi	Intravenous	60 ± 10 minutes	PET/MR MR acquisition (dependent on available technology and local practice).	True whole-body field of view recommended (skull vertex to feet). Dedicated MRI of the primary tumor can be performed during the uptake phase.