Table 4.
Postoperative changes in pituitary function and metabolic parameters in the 60 patients with postoperative assessments
| Baseline | A year after pituitary surgery | P | |
|---|---|---|---|
| hs-CRPa, ng/mL | 503 (242-1168) | 609 (277-1460) | .15 |
| BMI, kg/m2 | 23.8 ± 3.7 | 24.2 ± 3.8 | .05 |
| Systolic blood pressure, mm Hg | 120 ± 16 | 119 ± 16 | .41 |
| ASTa, U/L | 21 (19-27) | 22 (17-29) | .42 |
| ALTa, U/L | 18 (13-23) | 18 (13-27) | .70 |
| GGTa, U/L | 21 (13-39) | 21 (14-35) | .97 |
| HbA1c, % | 5.8 (5.5-6.0) | 5.8 (5.4-6.1) | .64 |
| HDL-cholesterola, mg/dL | 55 (46-62) | 56 (44-66) | .96 |
| LDL-cholesterola, mg/dL | 123 (106-143) | 117 (101-132) | .26 |
| Triglyceridea, mg/dL | 99 (82-146) | 115 (76-161) | .21 |
| Peak GH response to GHRP-2a, ng/mL | 8.9 (2.4-14.2) | 7.3 (2.1-16.3) | .28 |
| Severe GHD, N (%) | 30 (50) | 33 (55) | .37 |
| Corticotroph deficiency, N (%) | 20 (33) | 23 (38) | .44 |
| Free thyroxine, ng/mL | 1.01 ± 0.25 | 1.12 ± 0.19 | .001 |
| Hypothyroidism, N (%) | 20 (33) | 23 (38) | .44 |
| Hypogonadotropic hypogonadism, N (%) | 21 (35) | 19 (32) | .62 |
Data are presented as mean ± SD or median (interquartile range).
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; GGT, γ-glutamyl transpeptidase; GHD, GH deficiency; GHRP, GH-releasing peptide; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein.
a Values were log-transformed for analyses.