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(a) Fluorescence microscopy images of the cells stained for nuclei (blue) and MMP-13 (red) under different stimulate frequency. (b) Relative inflammation related genes expression of cells under increasing stimulation intensity. n = 3. (c,d) Relative inflammation related gene expression of cells under increasing stimulation frequency. n = 3. (e) Relative collagen related genes expression of cells under increasing stimulation frequency. n = 3. *, p < 0.05, **, p < 0.01. Scale bar, 100 μm.
