Table 2.
Patient characteristics | Portal vein thrombosis during follow-up (n = 155) | |||||
---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||||
HR | 95% CI | p value | HR | 95% CI | p value | |
Age (years) | 1.04 | 0.97–1.10 | 0.260 | |||
MELD (points) | 1.02 | 0.88–1.18 | 0.836 | |||
HVPG (mmHg) | 1.02 | 0.91–1.14 | 0.796 | |||
VWF-Ag (%) | 1.04 | 0.99–1.09 | 0.126 | |||
VWF-N (ng/mL) | 1.02 | 0.99–1.06 | 0.229 | |||
VWF-A (ng/mL) | 1.03 | 0.98–1.08 | 0.323 | |||
ADAMTS13-Act (per 10%) | 0.77 | 0.63–0.95 | 0.014 | – | – | – |
CRP (mg/dL) | 1.34 | 0.31–5.79 | 0.696 |
Statistical analysis: Cox proportional hazard models with backwards elimination were performed to assess risk factors for the incidence of portal vein thrombosis during follow-up. p values < 0.05 are indicated in bold
ADAMTS13 a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13, HVPG hepatic venous pressure gradient, MELD model of end stage liver disease, VWF-Ag von Willebrand factor antigen, VWF-N released N-terminal propeptide of VWF, VWF-A neoepitope of ADAMTS13-mediated degradation of VWF, CRP C-reactive protein