Table 2.
a,b Parameters associated with the clinical long-term outcome in univariate and multivariate analysis Cox-regression model—(all patients), (patients with cirrhosis)
| Parameter | Significance (univariate) | Significance (multivariate) |
|---|---|---|
| a Parameters associated with the clinical long-term outcome in univariate and multivariate analysis Cox-regression model (all patients) | ||
| HDV pos | p < 0.01; HR: 3.58; 95% CI 2.22–5.92 | p < 0.01; HR: 3.03; 95% CI 1.42–6.39 |
| Age (linear) | p < 0.01; HR: 1.10; 95% CI 1.04–1.08 | p < 0.01; HR: 1.10; 95% CI 1.00–1.13 |
| Gender (male) | p = 0.04; HR: 1.77; 95% CI 1.11–2.89 | p = 0.05; HR: 2.12; 95% CI 1.00–4.54 |
| Cirrhosis | p < 0.01; HR: 11.6; 95% CI 6.82–19.7 | Not significant |
| gGT (linear) | p < 0.01; HR: 1.00; 95% CI 1.00–1.01 | p < 0.01; HR: 1.00; 95% CI 1.00–1.10 |
| Alcalic phosphatase (linear) | p = 0.01; HR: 1.00; 95% CI 1.00–1.01 | p < 0.01; HR: 1.00; 95% CI 1.00–1.10 |
| Bilirubin (linear) | p < 0.01; HR: 1.00; 95% CI 1.00–1.01 | Not significant |
| Albumin (linear) | p < 0.01; HR: 0.87; 95% CI 0.81–0.93 | p < 0.01; HR: 0.93; 95% CI 0.82–0.94 |
| Platelets (linear) | p < 0.01; HR: 0.98; 95% CI 0.98–0.99 | p < 0.01; HR: 0.98; 95% CI 0.98–0.99 |
| INR | p < 0.01; HR: 55.5; 95% CI 27.4–112.1 | p < 0.01; HR: 9.93; 95% CI 2.24–46.2 |
| HBeAg negative | p < 0.01; HR: 3.49; 95% CI 1.61–7.58 | Not significant |
| Therapy (NA) | p < 0.01; HR: 1.92; 95% CI 1.18–2.91 | Not significant |
| Therapy (IFN) | p < 0.01; HR: 0.51; 95% CI 0.32–0.83 | Not significant |
| b Parameters associated with the clinical long-term outcome in univariate and multivariate analysis Cox-regression model (patients with cirrhosis) | ||
| Age (linear) | p < 0.01; HR: 1.03; 95% CI 1.01–1.06 | Not significant |
| gGT (linear) | p < 0.01; HR: 1.00; 95% CI 1.00–1.01 | p = 0.02; HR: 1.03; 95% CI 1.00–1.01 |
| Alcalic phosphatase (linear) | p = 0.01; HR: 1.01; 95% CI 1.01–1.02 | p < 0.01; HR: 1.01; 95% CI 1.00–1.02 |
| Bilirubin (linear) | p < 0.01; HR: 1.01; 95% CI 1.01–1.02 | Not significant |
| Albumin (linear) | p < 0.01; HR: 0.89; 95% CI 0.86–0.93 | p = 0.02; HR: 0.93; 95% CI 0.82–0.91 |
| Platelets (linear) | p < 0.01; HR: 0.99; 95% CI 0.98–0.99 | p = 0.02; HR: 0.99; 95% CI 0.98–0.99 |
| INR | p < 0.01; HR: 14.6; 95% CI 6.07–34.9 | p = 0.04; HR: 4.68; 95% CI 1.12–19.59 |
| Therapy (IFN) | p < 0.01; HR: 0.32; 95% CI 0.17–0.57 | Not significant |
| Therapy (NA) | p = 0.02; HR: 1.72; 95% CI 1.11–2.68 | Not significant |