Table 2.
Application of Long-Pulse Alexandrite Laser in Pigmented Lesions
| Author | Aim | Parameters | Outcomes |
|---|---|---|---|
| Trafeli et al28 | Lentigo and Freckle | Pulse duration: 3–60ms Spot size: 10mm Fluence: 9–88J/cm2 |
Optimal overall lesion clearance up to 76%-99% after 1 treatment |
| Ho et al29 | Lentigo and Freckle | Pulse duration: 100μs Spot size: 4mm Fluence: 11–13J/cm2 |
Majority of patients reported moderate to marked improvement after 1 treatment |
| Ho et al30 | Lentigo and Freckle | Pulse duration: 3ms Spot size: 10mm Fluence: 25–30J/cm2 |
No significant improvement and 20% of PIH risk |
| Lee et al31 | Melasma | Pulse duration: 3ms Spot size: 8–12mm Fluence: 20–26J/cm2 |
>50% of improvement: 44% of patients (single treatment) |
| Lee et al32 | Melasma | Pulse duration: 0.5–1ms Spot size: 15mm Fluence: 60–80J/cm2 |
A 30.5% reduction in the mMASI score (2–4 treatments) |
| Kim et al33 | Seborrheic Keratosis | Pulse duration: 3ms Spot size: 6mm Fluence: 35J/cm2 |
A mean improvement score of 3.4 after a mean 1.1± 0.4 treatments |
| Choi et al34 | Becker’s Nevus | Pulse duration: 3ms Spot size: 15–18mm Fluence: 20–25J/cm2 |
>50% of clearance: 63.6% of patients (mean 3.9 treatments) |
| Choi et al35 | Becker’s Nevus | Pulse duration: 0.5–5ms Spot size: 5–20mm Fluence: 10–24J/cm2 |
>50% of clearance:75% of patients (2.0±1.0 treatments) |