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. 2023 Nov 17;16:5367–5383. doi: 10.2147/JIR.S431628

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© 2023 Liu et al.

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METTL1 was downregulated in SLE patient. (A) METTL1 mRNA expression between SLE (n=20) and HC (n=6) in GSE122459; (B) RT-qPCR for METTL1 mRNA expression in HC (n=18), SLE-AP (n=20) and SLE-SP (n=25); (C)Western blotting for METTL1 protein expression in HC (n=5) and SLE patients (n=8); (D) Quantitative analysis of METTL1 protein levels in HC (n=5), SLE-AP (n=5) and SLE-SP (n=3). Student’s unpaired two-tailed t test or Mann–Whitney test. Data are means ± SEM. *P < 0.05.

Abbreviations: METTL1, Methyltransferase like 1; SLE, Systemic lupus erythematosus; HC, Healthy controls; SLE-AP, SLE patients in active period; SLE-SP, SLE patients in stable period.