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. 2023 Nov 17;16:5367–5383. doi: 10.2147/JIR.S431628

Table 1.

Comparison of Clinical Characteristics Between SLE Patients with METTL1 Low and High Expression

Patients with METTL1 mRNA Low Expression (n=23) Patients with METTL1 mRNA High Expression (n=22) P
Female, n (%) 19 (82.61) 21 (95.45) 0.170
Vasculitis, n (%) 4 (17.39) 1 (4.55) 0.170
Myositis, n (%) 1 (4.35) 0 (0) 0.323
Fever, n (%) 7 (30.43) 5 (22.73) 0.559
Hypocomplementemia, n (%) 15 (65.22) 10 (45.45) 0.182
Pericarditis, n (%) 4 (17.39) 1 (4.55) 0.170
Pleuritis, n (%) 2 (8.70) 0 (0) 0.157
Oral ulcer, n (%) 3 (13.04) 2 (9.09) 0.673
Pneumonia, n (%) 1 (4.35) 1 (4.55) 0.974
Pyuria, n (%) 3 (13.04) 5 (22.73) 0.396
Proteinuria, n (%) 6 (26.09) 10 (45.45) 0.175
Hematuria, n (%) 6 (26.09) 3 (13.64) 0.297
Cylindruia, n (%) 4 (17.39) 0 (0) 0.127
Renal involvement, n (%) 10 (43.48) 9 (40.91) 0.862
Central nervous system involvement, n (%) 2 (8.70) 0 (0) 0.157
Arthritis, n (%) 9 (39.13) 6 (27.27) 0.399
Skin rash, n (%) 8 (34.78) 5 (22.73) 0.372
Anti-dsDNA, n (%) 7 (30.43) 1 (4.55) 0.060
Anti-SSA, n (%) 11 (47.83) 10 (45.45) 0.873
Anti-SSB, n (%) 1 (4.35) 1 (4.55) 0.974
Anti-Sm, n (%) 10 (43.48) 4 (18.18) 0.067
Anti-nRNP, n (%) 12 (52.17) 8 (36.36) 0.286
Anti-rRNP, n (%) 8 (34.78) 6 (27.27) 0.586
AuaA, n (%) 9 (39.13) 2 (9.09) 0.019
Anti-Histone, n (%) 5 (21.74) 3 (13.64) 0.477
ANA, n (%) 22 (95.65) 20 (90.91) 0.524
SLEDAI 13.52±13.46 6.68±6.61 0.038