Table 1.
The effect of different medications for depression on body weight.
| Depression | |||||
|---|---|---|---|---|---|
| Medication Group | Medication | Weight Gain | Weight Neutral | Weight Loss | Reference |
| SSRIs | Fluoxetine | X∗ | X∗ | X∗∗ | [62,63] |
| Citalopram, sertraline, escitalopram | X | X | [55] | ||
| Paroxetine | X | [55] | |||
| SNRIs | All | X | [62,64] | ||
| TCAs | All | X | X | [68] | |
| MAOIs | All | X | [74] | ||
| Atypical Antidepressants | Mirtazapine | XX | [64,77] | ||
| Trazodone | X | X | [78] | ||
| Bupropion | XX | [100] | |||
| Vortioxetine | X | [91] | |||
Title: The effect of different medications for depression on body weight.
X: <5% of total body weight change; XX: ≥5% of total body weight change; ∗: Long-term (>4 months); ∗∗:Short-term (4–12 weeks).
SSRIs: Selective Serotonin Reuptake Inhibitors; SNRIs: Serotonin-Norepinephrine Reuptake Inhibitors; TCAs: Tricyclic Antidepressants; MAOIs: Monoamine Oxidase Inhibitors.