Table 13.
1. | Low serum vitamin D status in US adolescents has been found to be strongly associated with hyperglycemia, hypertension, and metabolic syndrome, with a relationship independent of adiposity. |
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2. | Deficiency of vitamin D is defined by the Institute of Medicine and Endocrine Society clinical practice guidelines as serum 25-hydroxyvitamin D [25(OH)D] < 20 ng/mL. |
3. | Treatment includes supplementation with vitamin D for at least 6 weeks or until acceptable blood levels are reached. |
4. | Children with obesity, malabsorptive syndromes, or taking medications affecting vitamin D metabolism may require larger doses to achieve the same serum levels as children without these conditions. |