Table 4.

Effect of mood stabilizing medications on body weight [3]. Wide variance exists in individual weight responses to psychiatric medications. Relatively few studies have directly compared individual drugs within the context of a prospective, randomized, controlled, dedicated body weight trial. Given the lack of available data and variance of data, it is challenging to objectively rank medications within a class, regarding their effects on body weight. Listed are mood stabilizing medications described to be especially associated with weight gain. Mood stabilizing medications with variable effects on body weight include lamotrigine and oxcarbazepine.

Mood stabilizing medications	Effect on body weight
Gabapentin	↑
Divalproex	↑
Lithium	↑
Valproate	↑
Vigabatrin	↑
Cariprazine	↑
Carbamazepine	↑