Table II.
Differential diagnosis of parkinsonism and frontal gait disorder with a visual inspection of posture and gait.
Parkinson’s disease | Atypical parkinsonism | Frontal gait disorder | |
---|---|---|---|
Stance and posture | Forward stoop, rest tremor | Extended neck and back Dystonic (axial) in some | Upper body spared. Wide based |
| |||
Ignition failure | Late | Early | Very early |
| |||
Arm swing | Reduced (asymmetric) | Reduced to normal (symmetric) | Compensatory superfluous movements |
| |||
Stride length | Short | Shorter | Very short |
| |||
Stance phase | Variable | Longest | Long |
| |||
Gait speed | Progressively rapid (festination) | Slower than Parkinson’s disease | |
| |||
Cadence | Higher | Relatively less | None |
| |||
Falls | Late | Early | Early |
| |||
Freezing of gait | Late | Common | Very common |
| |||
Apraxia of gait | Rare | Variable frequency | Common |
| |||
Primary anatomical substrate | Nigrostriatal pathmway | Basal ganglia, thalamus, midbrain | The supplementary motor area, premotor area, medial frontal gyrus, and frontal subcortical connections |