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. Author manuscript; available in PMC: 2023 Nov 21.
Published in final edited form as: Brain Behav Immun. 2022 Feb 14;102:110–123. doi: 10.1016/j.bbi.2022.02.008

Fig. 4. PEA counteracts hypothalamic injury in HFD-induced obese mice.

Fig. 4.

The mRNA transcription of (A) Nfkb1, (B) Il1b, (C) Crh, and (D) Crhr1 in the hypothalamus (n = 5 per group). Immunohistochemical evaluations and morphometric analyses of (E) the number of IBA1-positive microglial cells and (F) GFAP immunoreactive area in the hypothalamic arcuate nucleus (Arc) (n = 5 per group). 3 V, third ventricle, ME, median eminence. All data are shown as mean ± S.E.M. *p < 0.05, **p < 0.01, and ****p < 0.0001.