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. Author manuscript; available in PMC: 2023 Nov 21.
Published in final edited form as: Brain Behav Immun. 2022 Feb 14;102:110–123. doi: 10.1016/j.bbi.2022.02.008

Fig. 5. PEA limits neuroinflammation, astrogliosis and microgliosis in the hippocampus of HFD mice.

Fig. 5.

The mRNA expression of (A) Tnf and (B) Il1b in the hippocampus of all experimental groups (n = 5 per group). The immunohistochemical analyses of Iba1-positive microglial cells and GFAP-positive astrocytes in (C) the DG and (F) stratum radiatum (n = 5 per group). The count of the number of positive cells for (D, G) Iba1 and (E, H) of GFAP immunoreactive in DG and stratum radiatum, respectively (n = 5 per group). Hil, hilus of the DG; Py, pyramidal cell layer; LMol, lacunosum molecular layer. All data are shown as mean ± S.E.M. *p < 0.05, **p < 0.01, and ***p < 0.001.