Scheme of a mitochondrion shows four different mitochondrial localizations—outer mitochondrial membrane, intermembrane space, inner mitochondrial membrane, matrix—and the distribution of mitochondrial proteins contained in and classified by the MitoCarta3.0 database. Bar graphs for each individual tissue show the precentral distribution of mitochondrial proteins (left), phosphoproteins (middle), and STY sites (right) across different mitochondrial localizations. Fitting of outer mitochondrial membrane proportions to a beta-regression model shows significant differences between protein-phosphoprotein and protein-STY sites for all tissues (adjusted P-value < 0.0001) (see the Materials and Methods section and SourceDataForFigure6). Skeletal muscle (SKM), brown adipose tissue (BAT).
Source data are available for this figure.