Table 3.
Pathway enrichment of expression quantitative trait loci hotspots.
| Hotspot | KEGG pathwaya | No. genes in hotspot | ||
|---|---|---|---|---|
| Plant-pathogen interactions | Isoflavonoid | Phenylpropanoid | ||
| GM_1 | 175*** | 3 | 1 | 23,919 |
| GM_1_B | 16* | 1 | 0 | 2,136 |
| GM_2 | 2 | 0 | 0 | 578 |
| GM_2_B | 115* | 2 | 0 | 16,909 |
| GM_5 | 5 | 0 | 0 | 423 |
| GM_8 | 1 | 0 | 0 | 44 |
| GM_8_A | 2 | 0 | 0 | 367 |
| GM_8_B | 1 | 0 | 0 | 119 |
| GM_11 | 115*** | 5** | 0 | 14,081 |
| GM_12_A | 1 | 0 | 0 | 233 |
| GM_12_B | 79 | 1 | 0 | 13,736 |
| GM_12_C | 1 | 0 | 0 | 84 |
| GM_13 | 51*** | 2 | 0 | 6,889 |
| GM_15 | 174** | 4 | 1 | 25,727 |
| GM_15_A | 2 | 0 | 0 | 164 |
| GM_15_B | 2 | 0 | 0 | 186 |
| GM_17_D | 1 | 0 | 0 | 303 |
| GM_17 | 40 | 2 | 1 | 6,966 |
| GM_18 | 1 | 0 | 0 | 91 |
| GM_18_A | 1 | 0 | 0 | 88 |
| Mock GM_18 | 1 | 0 | 0 | 55 |
| No. genes in pathway | 314 | 17 | 297 | |
aGene list derived from the KEGG pathway database (accessed, February 2018; http://www.genome.jp/kegg/pathway.html); of the six pathways assessed, only those with genes represented by e-traits within hotspots are shown.
*p-value < 0.05, **p-value < 0.001, ***p-value < 0.0001—levels of significance (Fisher’s exact test with Benjamini–Hochberg correction; Fisher, 1935; Benjamini and Hochberg, 1995).