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. 2023 Nov 20;13:20304. doi: 10.1038/s41598-023-47496-9

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© The Author(s) 2023, corrected publication 2023

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Topology of different evolutionary trees for the 3,000,055 superfamily. The colour-coded branches denote distinct families. (a) The phylogenetic tree generated using SD. (b) The reference evolutionary tree constructed on the basis of the structural evolutionary distance TM-score. (c) The evolutionary tree derived from pairwise sequence alignment-based evolutionary distance MMseq2. (d) The phylogenetic tree obtained using the ML method in IQ-Tree.