TABLE 3.

Sensitivity and Specificity of Detection of Metastases by Radiologists Reading With or Without ML Support

	Specificity			Difference in Proportions			Sensitivity			Difference in Proportions
Site	n	ML	No ML	∆	LCI	UCI	n	ML	No ML	∆	LCI	UCI
Liver	165	98.2%	98.2%	0.0%	−2.4	2.4	23	60.9%	69.6%	−8.7%	−20.2	2.8
Lung	178	95.5%	95.5%	0.0%	−2.7	2.7	10	10.0%	0.0%	10.0%	−8.6	28.6
Adrenal	184	98.4%	96.7%	1.6%	−0.2	3.5	4	50.0%	50.0%	0.0%	0.0	0.0
Kidney	187	100.0%	100.0%	0.0%	0.0	0.0	1	0.0%	0.0%	0.0%	0.0	0.0
Brain	182	98.9%	98.9%	0.0%	0.0	0.0	6	66.7%	50.0%	16.7%	−13.2	46.5
Pleura	187	97.3%	97.9%	−0.5%	−2.9	1.8	1	0.0%	0.0%	0.0%	0.0	0.0
Spleen	188	100.0%	100.0%	0.0%	0.0	0.0	NA
Pancreas	188	100.0%	100.0%	0.0%	0.0	0.0	NA
Peritoneum	185	97.8%	98.4%	−0.5%	−1.6	0.5	3	0.0%	33.3%	−33.3%	−86.7	20.0
Bowel	188	99.5%	99.5%	0.0%	−1.5	1.5	NA
Chest	188	100.0%	100.0%	0.0%	0.0	0.0	NA
Pelvis (nonskeletal)	186	99.5%	100.0%	−0.5%	−1.6	0.5	2	0.0%	0.0%	0.0%	0.0	0.0
Skull	187	100.0%	100.0%	0.0%	0.0	0.0	1	0.0%	0.0%	0.0%	0.0	0.0
Cervical spine	188	100.0%	100.0%	0.0%	0.0	0.0	NA
Thoracic spine	184	99.5%	100.0%	−0.5%	−1.6	0.5	4	25.0%	0.0%	25.0%	−17.4	67.4
Lumbar spine	184	99.5%	98.9%	0.5%	−0.5	1.6	4	25.0%	0.0%	25.0%	−17.4	67.4
Sternum	187	100.0%	100.0%	0.0%	0.0	0.0	1	100.0%	100.0%	0.0%	0.0	0.0
Pelvis (skeletal)	186	99.5%	100.0%	−0.5%	−1.6	0.5	2	0.0%	50.0%	−50.0%	−119	19.3
Clavicle	NA						NA
Ribs	188	100.0%	100.0%	0.0%	0.0	0.0	NA
Other skeletal	188	100.0%	100.0%	0.0%	0.0	0.0	NA

Per-site, for experienced WB-MRI readers.

ML, machine learning.