Table 2.

Grading system for allergic reactions and anaphylaxis based on the Common Terminology Criteria for Adverse Events (CTCAE) v.5.0.

	Allergic reaction	Anaphylaxis
Grade	Clinical symptoms
0	No reaction	No reaction
1	Systemic intervention not indicated	-
2	Oral intervention indicated	-
3	Bronchospasm, hospitalization indicated for clinical sequelae; intravenous intervention indicated	Symptomatic bronchospasm, with or without urticaria, parenteral intervention indicated: allergy-related edema/angioedema, hypotension
4	Life-threatening consequences: urgent intervention indicated	Life-threatening consequences: urgent intervention indicated
5	Death	Death