Table 3.
N (47) | % | ||
---|---|---|---|
Age* | 53 ± 13 | 27–80 | |
Body mass index* | 29.6 ± 5.5 | 20.0–41.6 | |
BRCA mutation | 9 | 19.1 | |
Comorbidities | 21 | 43.7 | |
History of drug allergy | 6 | 12.7 | |
Histology | Serous (high-grade) | 42 | 89.4 |
Non-serous | 5 | 10,6 | |
Desensitization decide | History of prior HSR | 24 | 51 |
Positive CP skin test | 23 | 49 | |
Stage at diagnosis | 1–2 | 4 | 8.6 |
3–4 | 43 | 91.4 | |
Neo-adjuvant chemotherapy | Yes | 12 | 25.5 |
No | 35 | 75 | |
Number of CP cycle develop HSR: median (range) | 9.6 ± 2.3 | 7–14 | |
Cycles of desensitization treatment | 11.0 ± 8.5 | 3–36 | |
Success desensitization rate | 478 of total 496 cycles, 96.3% |
CP = carboplatin, HSR = hypersensitivity reaction.