Table 1.
Demographics, Rating Scales, and Sleep-Wake Measures in Healthy Controls, Primary Insomnia, and Major Depression.
| Healthy Controls (Mean (SD)) (n = 25) | Primary Insomnia (Mean (SD)) (n = 24) | Mayor Depressive Disorder (Mean (SD)) (n = 51) | |
|---|---|---|---|
|
| |||
| Demographics | |||
| Age, y | 33.9 (14.6) | 39.5 (14.2) | 33.2 (14.4) |
| Sex (F:M) | 17:8 | 17:7 | 33:18 |
| BMI, kg/m | 22.7 (3.2) | 24.4 (4) | 23.6 (4.1) |
| Rating Scales | |||
| Insomnia Severity Index | 1.32 (1.57) | 17.58 (2.80) | 14.86 (5.86) |
| HAM-D (without sleep items) | 0.44 (0.71) | 1.92 (1.74) | 16.49 (4.07) |
| Beck Depression Inventory1 | 2.21 (0.98) | 5.13 (2.80) | 23.55 (7.68) |
| Anhedonia | 0.16 (0.37) | 0.54 (0.88) | 4.37 (1.91) |
| Pittsburgh Sleep Quality Index | 1.56 (1.33) | 10.58 (2.10) | 9.67 (3.56) |
| DBAS 162 | 2.73 (1.26) | 4.70 (1.22) | 5.14 (1.47) |
| Perceived Stress Scale3 | 18.5 (2.47) | 18.61 (3.46) | 22.43 (4.07) |
| Fatigue Severity Scale4 | 2.12(0.85) | 3.48 (1.31) | 4.57 (1.19) |
| Sleep-Wake Diaries | |||
| Sleep Onset Latency, min | 11.62 (6.27) | 38.37(21.23) | 37.98 (30.81) |
| Wake After Sleep Onset, min | 9.18(7.41) | 68.29 (39.40) | 31.16(30.75) |
| Total Sleep Time, hours | 7.80 (0.54) | 5.55 (0.88) | 6.52 (1.21) |
| Sleep Efficiency. % | 93.44 (2.68) | 69.65 (9.27) | 80.87(11.65) |
| VAS SIecp Quality | 73.57(11.62) | 38.70 (10.03) | 47.98 (15.68) |
| Polysomnography | |||
| Apoca/Hypopnea Index | 0.94 (1.43) | 3.23 (9.49) | 2.68 (5.51) |
| LPS, min | 14.22 (19.21) | 26.23 (29.22) | 41.23(38.89) |
| SOI min* | 11.20(19.48) | 18.38 (22.41) | 3S.37 (32.49) |
| Wake After Sleep Onset, min | 44.16 (36.62) | 87.50 (88.55) | 61.48 (57.30) |
| Total Sleep Time, hours5 | 7.59 (0.72) | 6.09 (1.72) | 6.79 (1.18) |
| Sleep Efficiency, % | 89.47 (7.26) | 78.17 (17.72) | 81.18(10.18) |