Figure 1. Prevalence of Psychiatric Morbidity Among Patients With MS and Controls in the Administrative and Clinical Cohorts in the 5 Years Before MS Onset.

In the administrative cohort, an individual's first demyelinating disease-related claim represented MS onset. In the clinical cohort, MS onset was defined as the date of MS symptom onset, as recorded by an MS neurologist. The period represents the 5-year period before MS onset (e.g., −5 reflects the fifth year before MS onset and −1 the year before MS onset). MS = multiple sclerosis.