Skip to main content
. 2023 Nov 14;101(20):e1960–e1969. doi: 10.1212/WNL.0000000000207852

Figure 3. Mediation Mendelian Randomization Association Between Genetically Determined Estimated Glomerular Filtration Rate and Large Artery Stroke, Controlling for Systolic Blood Pressure.

Figure 3

Directed acyclic graph demonstrating the total, direct, and indirect effects of estimated glomerular filtration rate on large artery stroke risk as well as the proportion of the total effect mediated by systolic blood pressure. Shown are the results derived from inverse-variance weighted Mendelian randomization analysis. eGFR = estimated glomerular filtration rate; SBP = systolic blood pressure.