Table 4.
Acute Model Diagnostic Performance
| UCH-L1 | GFAP | IL-6 | GFAP + UCH-L1 | UCH-L1 + IL-6 | GFAP + IL-6 | GFAP + UCH-L1 + IL-6 | |
| Tjur R2 | 0.23 (0.08–0.40) | 0.31 (0.15–0.48) | 0.50 (0.34–0.64) | 0.35 (0.17–0.50) | 0.51 (0.39–0.64) | 0.54 (0.34–0.68) | 0.54 (0.34–0.67) |
| AIC | 130 (106–151) | 116 (94–139) | 88 (68–112) | 114 (91–142) | 88 (69–112) | 85 (65–112) | 86 (68–117) |
| BIC | 136 (114–158) | 122 (101–145) | 93 (73–118) | 122 (101–149) | 96 (77–121) | 93 (73–122) | 97 (79–126) |
Abbreviations: AIC = Akaike Information Criterion; BIC = Bayesian Information Criterion; GFAP = glial fibrillary acidic protein; IL = interleukin; UCH-L1 = ubiquitin carboxy-terminal hydrolase L1.
Models were arranged in ascending order based on their Tjur R2 value, which is a method of calculating the coefficient of determination for generalized linear models with binary outcomes. 95% CIs for each model were calculated using bootstrapping.