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. 2023 Nov 21;101(21):e2114–e2125. doi: 10.1212/WNL.0000000000207716

Figure 4. CLDN23 Associations Have Larger Effect Sizes Within 6 Months of Enrollment vs Later.

Figure 4

Shows the estimates and 95% confidence intervals of the interaction of the study time points 1–6 months vs 6–24 months with each suggestive SNP found in chromosome 8. Interestingly, the interaction estimates of many SNPs seem to straddle one, with SNP estimates at 1–6 months having greater odds of motor recovery. In comparison, SNP estimates at 6–24 months have less odds of motor recovery. SNP = single nucleotide polymorphism