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. 2023 Jul 19;29(6):811–828. doi: 10.1093/humupd/dmad018

Table 2.

Results for fertility outcomes stratified by nutritional component in women conceiving via ART.

Category Studies Live birth Clinical pregnancy Implantation Fertilization rate IVF-specific (embryo and oocyte characteristics)
ENERGY AND MACRONUTRIENTS

Protein 1
  • +ve: increasing quartiles of fish, also when replacing other meat, other protein-rich food (Nassan et al., 2018).

  • NS: total meat intake, eggs, vegetable source of protein (Nassan et al., 2018).

NS: total meat intake, eggs, vegetable source of protein (Nassan et al., 2018). NS: total meat intake, eggs, vegetable source of protein (Nassan et al., 2018).
CHO 1 NS: total CHO (Noli et al., 2020). NS: total CHO Noli et al. (2020). NS: embryo transfer: total CHO (Noli et al., 2020).
GI/GL 1 NS: Noli et al. (2020). NS: Noli et al. (2020). NS: embryo transfer (Noli et al., 2020).
Fats and FAs 1 NS: all fats and fatty acids (Salas-Huetos et al., 2022). NS: all fats and fatty acids (Salas-Huetos et al., 2022).

CORE FOOD GROUPS

Dairy 1
Whole grains 2 NS: Noli et al. (2020).
Fish/seafood 1 +ve: Q1 vs Q4 total fish consumption (Salas-Huetos et al., 2022). NS: total fish consumption (Salas-Huetos et al., 2022). NS: total fish consumption (Salas-Huetos et al., 2022).
Fruits and vegetables 1

DISCRETIONARY FOODS

Sugar-sweetened beverages 1 +ve: Reducing cups of sugared soda/day (Machtinger et al., 2017).

PHYTOESTROGENS

Soy and other 1 +ve: any soy isoflavone intake vs none (Vanegas et al., 2015). +ve: any soy isoflavone intake vs none (Vanegas et al., 2015). NS: soy isoflavone intake (Vanegas et al., 2015). +ve: any soy isoflavone intake vs none (Vanegas et al., 2015).
WHOLE DIETS

Fertility diet 1 NS (Gaskins et al., 2019). NS (Gaskins et al., 2019). NS (Gaskins et al., 2019).
MedDiet/aMedDiet 5 NS (Vujkovic et al., 2010).
Profertility diet 1 +ve: increasing dietary adherence (Gaskins et al., 2019). +ve: increasing dietary adherence (Gaskins et al., 2019). +ve: increasing dietary adherence (Gaskins et al., 2019).
aHEI-2010 1 NS (Gaskins et al., 2019). NS (Gaskins et al., 2019). NS (Gaskins et al., 2019).
Healthy diet/unhealthy diet 1 NS (Jahangirifar et al., 2019). +ve: total oocytes: T3 vs T1 dietary adherence (Jahangirifar et al., 2019).
DII 1 NS (Diba-Bagtash et al., 2021).

aHEI-2010, alternative healthy eating index 2010; aMED, alternative Mediterranean diet; CHO, carbohydrates; DHA, docosahexaenoic acid; DII, dietary inflammatory index; EPA, Eicosapentaenoic acid; FAs, fatty acids; GI/GL, glycemic index/glycemic load; MedDiet, Mediterranean diet; NS, not significant; −ve/+ve, negative/positive; SSB, sugar sweetened beverages.