Fig. 7. MD simulations of the Aβ42 antiparallel C-sheet tetramers in SDS and DPC micelles.

a Initial structure in an SDS micelle. b Snapshot in SDS at 869.3 ns of a simulation. c Initial structure in a DPC micelle. d Snapshot in DPC at 500.0 ns. The micelles are shown in surface representation with headgroups in yellow and hydrocarbon tails in grey. Aβ42 molecules are shown in cartoon representation with residues 1 to 29 in cyan and residues 30-42 in red.