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. 2023 Nov 21;14:7581. doi: 10.1038/s41467-023-43139-9

Fig. 4. Local microcircuit motif computations explain heterogeneity of cerebellar cortical responses.

Fig. 4

a Motif representations of feedforward and recurrent connectivity between Purkinje cells (PCs) and molecular layer interneurons (MLIs) alongside examples of parallel fiber (PF, filled black triangle) and climbing fiber (CF, unfilled black triangle) inputs. b Illustrations of local cerebellar network anatomy with feedforward and recurrent connections between Purkinje cells (PC) and molecular layer interneurons (MLIs). c TRACENet predictions for Purkinje cells connected in feedforward and recurrent patterns with MLIs and PCs for the Narrow (blue) and Wide (green) conditions. Below: Purkinje cell rasters and firing rates are shown for the Narrow (blue) and Wide (green) conditions for paired (blue/green) and test trials (gray). d TRACENet predictions for MLIs connected in feedforward patterns with PCs for the Narrow (blue) and Wide (green) conditions. Below: Putative MLI rasters and firing rates are shown for the Narrow (blue) and Wide (green) conditions for paired (blue/green) and test trials (gray).