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. 2023 Oct 24;31:101142. doi: 10.1016/j.omtm.2023.101142

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© 2023 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Correlation between VP stoichiometry and transduction efficacy

(A–C) Plot of VP molar stoichiometry and transduction efficiency of Bulk, F1.1, F2.2, rAAV2-M203V, and -M211V. Relative potencies indicate GFP-positive viable cell counts at MOI 1 × 10², all normalized to the bulk state WT value of 1. Error bars represent ± SD for three independent wells in the GFP reporter gene assay. (A) Correlation between VP1 stoichiometry and relative potency. (B) Correlation between VP2 stoichiometry and relative potency. (C) Correlation between the total stoichiometry of VP1 and VP2 and relative potency.