EnnA inhibits cancer cell lines proliferation in vitro
(A) Survival of human breast (MCF7, MDA-MB-453, Hs578T, MDA-MB-231) and murine (E0771 and 4T1) cancer cells upon treatment with EnnA for 48 h. Data are represented as mean ± S.E.M. and represent at least three independent studies.
(B) Western blot analyses for the indicated proteins using lysates from the cell types in A treated with DMSO, 0.5 μM 17-AAG, and EnnA (at EC50 concentrations determined in A).