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. 2023 Nov 7;14:1215755. doi: 10.3389/fendo.2023.1215755

Table 2.

The pooled results of the forest plot for clinical outcomes.

Clinical outcomes Study (n) Case (n) RR/SMD/MD 95% CI p I2 (%) Model
Clinical pregnancy rate 7 593 1.63 [1.31, 2.03] < 0.0001 0 Fixed
Number of oocytes retrieved 8 706 0.91 [0.47, 1.35] < 0.0001 90 Random
Optimal embryos rate 3 234 1.84 [1.30, 2.59] 0.0005 0 Fixed
Number of optimal embryos 4 375 0.28 [0.08, 0.48] 0.005 94 Random
Cycle cancellation rate 3 299 0.46 [0.24, 0.89] 0.02 0 Fixed
Cleavage rate 4 353 1.12 [0.99, 1.27] 0.07 51 Random
Fertilization rate 5 665 1.33 [1.18, 1.50] < 0.00001 48 Fixed
Embryo implantation rate 3 430 1.56 [1.21, 2.01] 0.0006 17 Fixed
Miscarriage rate 5 261 1.02 [0.50, 2.10] 0.95 0 Fixed
E2 on the day of hCG 7 602 1.18 [0.46, 1.91] 0.001 94 Random
Endometrial thickness on the day of hCG 5 449 0.75 [0.41, 1.09] < 0.0001 57 Random
Total days of Gn used 5 438 -0.26 [-0.46, -0.06] 0.01 42 Fixed
Total dose of Gn used 6 538 -460.97 [-617.20, -304.73] < 0.00001 90 Random

Gn, gonadotropin; E2, estradiol.