Table 2.
Clinical outcomes | Study (n) | Case (n) | RR/SMD/MD 95% CI | p | I2 (%) | Model |
---|---|---|---|---|---|---|
Clinical pregnancy rate | 7 | 593 | 1.63 [1.31, 2.03] | < 0.0001 | 0 | Fixed |
Number of oocytes retrieved | 8 | 706 | 0.91 [0.47, 1.35] | < 0.0001 | 90 | Random |
Optimal embryos rate | 3 | 234 | 1.84 [1.30, 2.59] | 0.0005 | 0 | Fixed |
Number of optimal embryos | 4 | 375 | 0.28 [0.08, 0.48] | 0.005 | 94 | Random |
Cycle cancellation rate | 3 | 299 | 0.46 [0.24, 0.89] | 0.02 | 0 | Fixed |
Cleavage rate | 4 | 353 | 1.12 [0.99, 1.27] | 0.07 | 51 | Random |
Fertilization rate | 5 | 665 | 1.33 [1.18, 1.50] | < 0.00001 | 48 | Fixed |
Embryo implantation rate | 3 | 430 | 1.56 [1.21, 2.01] | 0.0006 | 17 | Fixed |
Miscarriage rate | 5 | 261 | 1.02 [0.50, 2.10] | 0.95 | 0 | Fixed |
E2 on the day of hCG | 7 | 602 | 1.18 [0.46, 1.91] | 0.001 | 94 | Random |
Endometrial thickness on the day of hCG | 5 | 449 | 0.75 [0.41, 1.09] | < 0.0001 | 57 | Random |
Total days of Gn used | 5 | 438 | -0.26 [-0.46, -0.06] | 0.01 | 42 | Fixed |
Total dose of Gn used | 6 | 538 | -460.97 [-617.20, -304.73] | < 0.00001 | 90 | Random |
Gn, gonadotropin; E2, estradiol.