Figure 2.

Study Flowchart of Model Development, Testing, and External Application

Schematic representation of the scientific approach to the development of the deep-learning model, the validation of the model through internal and external cohorts, and the application of the automated epicardial adipose tissue (EAT) volume quantification tool to 3 groups of patients from the AdipoRedOx (Adipose tissue and cardiovascular RedOx regulation) study and SCOT-HEART (Scottish Computed Tomography of the Heart) trial. AF = atrial fibrillation; DLN = deep-learning network; other abbreviations as in Figure 1.