Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 22;21:453. doi: 10.1186/s12916-023-03158-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — Poor male fertility and sperm quality in RNase T2 KI mice. A The litter sizes of the pregnant females showed that the RNase T2 KI males had lower fertility than WT and control males (n = 4 to 18 per group according to the number of pregnant females). B, C CASA of sperm motility showed that RNase T2 KI males display poor sperm motility (B) and progressive motility (C) in comparison to WT and control males (n = 3). D RNase T2 KI sperm exhibited significantly higher sperm head deformity (n = 16). E Wright-Giemsa staining showed head deformed sperm in RNase T2 KI mice. Scale bar, 50 μm. F Electron microscopic analysis showed intumescent cytoplasm (see the indicated asterisks) and displaced acrosome (see the indicated arrows) in sperm head of RNase T2 KI sperm. Scale bar, 2 μm and 1 μm respectively. G Comparison of the fertilization rates in IVF and ICSI experiments. Data are expressed as means ± SD; *P < 0.05, **P < 0.01 and ***P < 0.001