Skip to main content
. 2023 Nov 22;3(11):e0002327. doi: 10.1371/journal.pgph.0002327

Fig 1. Algorithm of sampling from the study cohort and outline of the investigation.

Fig 1

A) The flow-chart outlining the cross-sectional study sampling for the LTBI cohort. The study recruited 76 volunteers by a random sampling method, the exclusion criteria’s as well as the IGRA reports (from a total of 172 individuals) who were further divided into three cohorts: Household contacts/IGRA+ve (HHC/IGRA+ve) (n = 26 from 58 positive individuals), household contacts/IGRA-ve (HHC/IGRA-ve) (n = 25 from 52 negative individuals) and healthy controls (HCs) (n = 25 from 44 individuals tested negative for LTBI). HCs were defined as having had no contact with active TB cases and were negative for IGRA. B) Blood was drawn in Lithium-heparin tubes and Sodium-citrate tubes. Plasma samples in the Lithium-heparin tubes were subjected to IGRA after transferring them to the QFT tubes. Plasma samples in the sodium-citrate tubes were subjected to Bio-Plex Luminex Cytokine assay.