Table 1. Clinico-demographic characteristics of the study cohort.
| Characteristics | HC | HHC/IGRA+ve | HHC/IGRA-ve | p value |
|---|---|---|---|---|
| Number | 25 | 26 | 25 | |
| Age, years, median (IQR) | 36 (29–47) | 39.5 (28–54.8) | 40 (33–47) | 0.492 |
| Gender, male, n (%) | 14 (56%) | 9 (34.6%) | 7 (28%) | 0.044* |
| BMI, median (IQR) | 25.4 (22.9–28.4) | 25.8 (23–30.23) | 24.7 (21.9–28.4) | 0.748 |
| BCG vaccination, n (%) | 21 (84%) | 21 (80.8%) | 20 (80%) | 0.379 |
| Residential area, urban, n (%) | 13 (52%) | 13 (50%) | 13 (52%) | 0.986 |
| Bilirubin, (mg/dl), median (IQR) | 0.7 (0.6–0.85) | 0.7 (0.6–0.83) | 0.6 (0.45–0.9) | 0.493 |
| SGOT, (U/L), median (IQR) | 25 (16–32) | 21.5 (18–26.5) | 20 (17–25.5) | 0.078† |
| SGPT, (U/L), median (IQR) | 25 (16–43.5) | 19.5 (16–26) | 19 (14–22.5) | 0.075† |
| ALP, (U/L), median (IQR) | 69 (51–74) | 69 (54.8–90.3) | 58 (49–73) | 0.109 |
| Creatinine, (mg/dl), median (IQR) | 0.8 (0.8–1.0) | 0.8 (0.7–0.9) | 0.8 (0.7–0.9) | 0.152 |
| Urea, (mg/dl), median (IQR) | 23 (20–34) | 22.5 (16.7–25.8) | 20 (17–23.5) | 0.052† |
|
Neutrophil count (10x3/μL), median (IQR) %, median (IQR) |
4.57 (4.07–5.31) 59.7 (52–63.5) |
4.4 (3.4–6.5) 60.6 (43.4–66.3) |
4.2 (3.7–5.53) 55.1 (50.5–62.9) |
0.693 0.954 |
|
Lymphocyte count (10x3/μL), median (IQR) %, median (IQR) |
2.44 (2.07–2.81) 29.6 (27.3–53.6) |
2.62 (2.07–3.32) 31.2 (25.1–39.6) |
2.2 (1.8–2.86) 31.1 (24.6–35.9) |
0.263 0.925 |
|
Monocyte count (10x3/μL), median (IQR) %, median (IQR) |
0.52 (0.43–0.65) 6.6 (5.6–7.8) |
0.57 (0.43–0.64) 6.85 (5.15–7.65) |
0.51 (0.41–0.7) 6.6 (5.8–9.1) |
0.974 0.828 |
|
Eosinophil count (10x3/μL), median (IQR) %, median (IQR) |
0.19 (0.11–0.27) 2.3 (1.35–4.25) |
0.25 (0.18–0.48) 3.55 (1.93–6.7) |
0.2 (0.4–0.39) 2.9 (1.65–5.05) |
0.166 0.189 |
|
Basophil count (10x3/μL), median (IQR) %, median (IQR) |
0.04 (0.03–0.06) 0.6 (0.45–0.8) |
0.05 (0.04–0.06) 0.6 (0.5–0.9) |
0.04 (0.03–0.06) 0.6 (0.5–0.75) |
0.384 0.719 |
|
Medical conditions,
n (%) Sickness past 14-days Diabetes mellitus Hypertension COPD/asthma Hemodialysis History of COVID-19 Smoking Alcohol |
6 (24%) 5 (20%) 6 (24%) 2 (8%) 2 (8%) 6 (24%) 2 (8%) 4 (16%) |
4 (15.4%) 8 (30.8%) 4 (15.4%) 2 (7.7%) 0 (0%) 4 (15.4%) 1 (3.85%) 2 (7.7%) |
4 (16%) 6 (24%) 4 (16%) 3 (12%) 2 (8%) 4 (16%) 0 (0%) 0 (0%) |
0.479 0.753 0.479 0.632 1.000 0.450 0.153 0.141 |
All categorical variable reported as numbers (n) and percentages (%), and continuous variables reported as median, IQR. HC, healthy control; HHC, household contact, IGRA, interferon gamma release assay; SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic-pyruvic transaminase; ALP, alkaline phosphatase. All continuous variables were compared using the Kruskal-Wallis test, whilst all the categorical variables were compared using Chi-Square test. *Represent p<0.05, †having a trend of significance.