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. 2023 Nov 7;14:1188087. doi: 10.3389/fimmu.2023.1188087

Figure 2.

Figure 2

Effects of the combination of verteporfin-PDT with 5-ADC on expression of DNA methylation regulators in 4T1 TNBC cell line. (A) Western blot of Dnmt1 and YAP in 4T1 TNBC cells treated with verteporfin-PDT and/or 5-ADC (0.5 µM) evaluated 48 h post-treatment. Concentrations of verteporfin tested at 1 J.cm-2 and 2.5 J.cm-2 were 0.25 μM and 0.15 μM respectively. (B) Immufluorescence staining of YAP in 4T1 cells treated with verteporfin-PDT and/or 5-ADC at 48h post-treatment.