Table 1. Demographic, anthropometric, clinical, and laboratory characteristics of the participants at the time of diagnosis (baseline).
(n = 46) | |
---|---|
Age at diagnosis (years) | 12.72 ± 6.44 (4-37) |
Females (n, %) | 23 (50%) |
Body weight (kg) | 42.11 ± 16.58 |
Height (m) | 1.50 ± 0.20 |
BMI (kg/m2) | 18.96 ± 3.53 |
BMI z-score | -0.60(±1.45) |
DKA at diagnosis (n, %) | 19 (41.3%) |
FPG (mg/dL) | 275.5 ± 117.9 |
HbA1c (%) | 10.67 ± 2.70 |
TDD (IU/kg of body weight/24h) | 0.49 ± 0.27 |
25(OH)D (ng/mL) | 32.41 ± 13.87 |
Fasting C peptide (ng/mL) | 0.82 ± 0.53 |
GADA antibody (IU/mL) (n = 46) | 37(80.4%)* |
Islet antigen-2 antibody (IA-2A) (IU/mL) (n = 3) | 2*(66.6%)* |
Insulin autoantibody (<7.3% binding) (n = 14) | 5*(35.7%)* |
Islet cell autoantibody (ICA - nonreactive) (n = 18) | 10*(55.5%)* |
Zinc transporter 8 autoantibody (ZnT8A – UA/mL) (n = 2) | 2*(100%)* |
Data are presented as mean ± standard deviation or frequency (percentage). Abbreviations: 25(OH)D, serum 25-hydroxyvitamin D levels; BMI, body mass index; DKA, diabetic ketoacidosis; FPG, fasting plasma glucose; GADA antibody, glutamic acid decarboxylase autoantibody; HbA1c, glycated hemoglobin; n, number of patients tested for the antibody; TDD, total daily insulin dose.
Number and % of patients tested who were positive for the antibody.