Table 3. Main studies analyzing the prevalence of clinical remission in children and adolescents with new-onset type 1 diabetes.

Study (Country)	n	Age (years)	(F/M) %	DKA %	PR %	DR (Months)	% PR 12 Months	%PR 24 Months	%IFCR 12 Months
Present study, Brazil	46	12.72	50/50	41.3	80.4	13.15	62	51.2	19.5
Camilo and cols., 2020, Brazil	51	10.1	50.9/49.1	29.3	41.2	7	33.3	7.84	0
Bektas and cols., 2020, Turkey	55	10.6	43.7/56.3	47	56.4	NR	21.8	5.5	0
Pecheur and cols., 2014, Belgium	242	8.8	47.5/52.5	25.6	56.2	9.2	28.4	7.5	0
Chiavaroli and cols., 2019, New Zealand	678	9.2	46.3/53.7	27.1	42.4	NR	10.6	7.1*	0
Nagl and cols., 2017, Germany and Austria	3657	7.9	49/51	15	61	9	28	13	0

Abbreviations: n: number of patients, age: mean or median age of the participants at each study, F: female; M, male; DKA: diabetic ketoacidosis; NR: not reported; PR: partial clinical remission at any time; DR: duration of remission; IFCR: insulin-free clinical remission. All studies used IDAA1c [HbA1c (%) + [4 × insulin dose (units per kilogram per 24 h)] to define the occurrence of partial clinical remission. An IDAA1c value ≤9 was considered indicative of partial clinical remission.

^*Data assessed at 18 months.