Table 2.
Clinical and outcome parameters.
| Extubation After SBT | YES 67 (49.63%) |
NO 68 (50.37%) |
Overall 135 (100%) |
p value |
|---|---|---|---|---|
| Respiratory parameters | ||||
| Before SBT | ||||
| FiO2 (%) | 26 (6) | 30 (8) | 28 (7) | 0.002 |
| PEEP (cm H2O) | 5.2 (1.0) | 5.2 (1.3) | 5.2 (1.1) | 0.99 |
| VT (mL/kg) | 7.5 (0.7) | 7.5 (0.7) | 7.5 (0.7) | 0.19 |
| P0.1 (cm H2O) | 1.7 (1.0) | 2.2 (1.6) | 2.0 (1.4) | 0.11 |
| Respiratory Rate (b/min) | 24 (6) | 26 (6) | 25 (6) | 0.02 |
| SpO2 (%) | 95 (3) | 94 (3) | 95 (3) | 0.002 |
| Heart Rate (b/min) | 89 (19) | 95 (20) | 92 (20) | 0.07 |
| SAP (mmHg) | 133 (24) | 133 (22) | 133 (23) | 0.94 |
| MAP (mmHg) | 88 (14) | 87 (14) | 88 (14) | 0.47 |
| EWSO2 | 17.9 (6.9) | 14.1 (5.8) | 16.0 (6.6) | 0.005 |
| SBT number | 2 (3) | 2 (2) | 2 (2) | 0.79 |
| During SBT | ||||
| O2 flow (L/min) | 2.6 (1.4) | 3.9 (1.9) | 3.2 (1.8) | < 0.0001 |
| Heart Rate (b/min) | 91 (17) | 101 (21) | 96 (20) | 0.008 |
| Respiratory Rate (b/min) | 26 (7) | 33 (8) | 29 (8) | < 0.0001 |
| SpO2 (%) | 95 (3) | 91 (5) | 93 (5) | < 0.0001 |
| SAP (mmHg) | 140 (27) | 145 (26) | 142 (27) | 0.25 |
| MAP (mmHg) | 93 (15) | 95 (17) | 94 (16) | 0.25 |
| EWSO2 | 14.8 (5.3) | 9.9 (4.4) | 12.4 (5.4) | < 0.0001 |
| After SBT | ||||
| O2 flow (L/min) | 4.1 (9.5) | NA | NA | NA |
| Heart Rate (b/min) | 94 (21) | NA | NA | NA |
| Respiratory Rate (b/min) | 25 (8) | NA | NA | NA |
| SpO2 (%) | 95 (3) | NA | NA | NA |
| SAP (mmHg) | 138 (23) | NA | NA | NA |
| MAP (mmHg) | 91 (16) | NA | NA | NA |
| EWSO2 | 9.8 (9.5) | NA | NA | NA |
| Outcomes | ||||
| Overall MV duration (days) | 7.0 (8.6) | 14.2 (13.3) | 10.5 (11.7) | 0.0004 |
| VFD in ICU (days) | 2.8 (3.2) | 3.4 (3.7) | 3.1 (3.5) | 0.29 |
| VFD at Day28 (days) | 21.6 (9.3) | 14.6 (10.8) | 18.1 (10.7) | 0.0001 |
| ICU LOS (days) | 13.5 (12.4) | 24.3 (16.9) | 18.8 (15.7) | < 0.0001 |
| Hs LOS (days) | 38.5 (41.8) | 39.8 (35.4) | 39.1 (38.6) | 0.85 |
| Reintubation ≤ 72h (n) | 14 (20.9%) | 19 (31.1%) | 33 (25.8%) | 0.26 |
| Reintubation ≤ Day7 (n) | 14 (20.9%) | 18 (29.5%) | 32 (25.0%) | 0.36 |
| Never Weaned (n) | 0 (0%) | 8 (12.1%) | 8 (6.0%) | 0.002 |
Results are presented as number (%). A p value equal or below 0.05 was considered statically significant and depicted in black tone.
SBT: Spontaneous Breathing Test; FiO2: inspiratory oxygen fraction; PEEP: positive end expiratory pressure; VT: volume tidal; P0.1: negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit; SpO2: pulse oximetry; SAP: systolic arterial pressure; MAP: mean arterial pressure; NIV: noninvasive ventilation; MV: mechanical ventilation; VFD: ventilatory free day; LOS: length-of-stay; Hs: hospital; NA: not applicable.
Significant values are in bold.